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A．the U.S. domestic anti-AIDS drug market is shrinking quickly
B．American drug makers have a lot of extra capital to invest
C．the bilateral deal has made U.S. investments much easier now
D．South Africa has a huge global market potential in these drugs
答案
更多“American drug makers want to get a share in the anti-AIDS drug production in South Africa”相关的问题
第1题
第2题
Now a huge collection of drug company internal documents—revealed as part of a lawsuit—offers a wealth of detail. In 1996, Dr. David Franklin, an employee of the drug company Parke-Davis, filed the lawsuit under federal whistleblower statutes alleging that the company was illegally promoting a drug called Neurontin for so called "off-label' uses. Under federal law, once the FDA approves a drug, a doctor can prescribe it for anything. But the law specifically prohibits the drug company from promoting the drug for any unapproved uses. In 2004, the company, by then a division of Pfizer admitted guilt and agreed to pay $430 million in criminal and civil liability related to promoting the drug for off-label use.
Spokespeople for Pfizer say that any wrong doing occurred before Pfizer acquired the company. But Pfizer fought hard to keep all the papers related to the suit under seal. A judge denied the request and they are now part of the Drug Industry Document Archive at the University of California, San Francisco.
What is most interesting is not the illegal actions they reveal, but the details of activities that are perfectly legal. And according to people familiar with the industry, the methods detailed in these company memos are routine.
One tactic identifies certain doctors as "thought leaders, "—those whose opinions influence the prescribing pattern of other doctors. Those whose views converge with the company goals are then showered with rewards, research and educational grants. In the Parke-Davis case 14 such big shots got between $10,250 and $158,250 between 1993 and 1997.
"Medical education drives this market", wrote the author of one Parke-Davis business plan in the files. Many state licensing boards require physicians to attend sessions in what is called continuing medical education (CME) to keep current in their field.
At one time, medical schools ran most CME courses. Now, an industry of medical education and communications committees (MECCs) run most of the courses. These companies with innocent sounding names like Medical Education Systems set up courses, sometimes in conjunction with medical meetings, at other times often in fancy restaurants and resorts. The drug companies foot the bill, with the program usually noting it was financed by an "unrestricted educational grant" from the company.
Using MECCs, Parke-Davis set up conference calls so that doctors could talk to one another about the drugs. The moderators of the calls, often thought leaders or their younger assistants, received $250 to $500 a call. Drug company reps were on the line, instructed to stay in a "listen only" mode, but monitoring to be sure the pitch met their expectations.
Clearly, 'many of the physicians in these schemes are not innocent bystanders. Whether it is ghost writing, making telephone calls to colleagues or leading a CME session, many of the doctors got paid well. Others received a free meal or transportation to a resort to listen to an "educational session".
Physicians often claim they are not influenced by payments from the pharmaceutical industry. But with the methods so thoroughly detailed in these papers, drug companies clearly believe they are getting their money's worth.
The drug companies are willing to pay leading doctors to
A．manipulate medical education sessions.
B．improve the individual health-care service.
C．have personal contact with physicians.
D．help promote the drugs they produce.
第3题
In both history and sociology, scholarly work on immigration was sparked by the great debates of the 1920s, as Americans argued over which immigrants to include and which to exclude from the American nation. The result of that particular great debate involved the restriction of immigration from Asia and southern and eastern Europe.
Reacting to the debates of their time, sociologists and historians nevertheless developed different central themes. While Chicago School sociologists focused on immigrant adaptation to the American mainstream, historians were more likely to describe immigrants engaged in building the American nation or its regional sub-cultures.
Historians studied the immigrants of the past, usually in the context of nation-building and settlement of the western United States, while sociologists focused on the immigrant urban workers of their own times—that is, the early 20th century. Meanwhile, sociologists' description of assimilation as an almost natural sequence of interactions resulting in the modernization, and Americanization of foreigners reassured Americans that their country would survive the recent arrival of immigrants whom longtime Americans perceived as radically different.
Historians insisted that the immigrants of the past had actually been the "makers of America"; they had forged the mainstream to which new immigrants adapted. For sociologists, however, it was immigrants who changed and assimilated over the course of three generations. For historians, it was the American nation that changed and evolved.
In current debates, overall, what seems to be missing is not knowledge of significant elements of the American past or respect for the lessons to be drawn from that past, but rather debaters' ability to see how time shapes understanding of the present.
In the first moments of American nation-building, the so-called Founding Fathers celebrated migration as an expression of human liberty. Here is a reminder that today's debates take place among those who agree rather fundamentally that national self-interest requires the restriction of immigration. Debaters disagree with each other mainly over how best to accomplish restriction, not whether restriction is the right course. The United States, along with many other nations, is neither at the start, nor necessarily anywhere near the end, of a long era of restriction.
Henry Ford's words are cited to______.
A．show the absurdity of history
B．indicate the significance of the history we make today
C．emphasize the role of immigrants in the U.S. history
D．introduce the debate on immigration worldwide
第4题
The race for a vaccine began after the first human case emerged in Hong Kong in 1997. Backed by the World Health Organization (WHO), three research teams in the US and UK are trying to create a seed virus for a new vaccine. Their task is formidable, but researchers remain optimistic". There are obstacles, but most of the obstacles have been treated sensibly", says Richard Webby, a virologist at St. Jude Children's Research Hospital in Memphis, Tennessee.
The biggest challenge is likely to be the rapidly mutating virus. Candidate vaccines produced last year against the H5N1 virus are ineffective against this year's strain. Scientists will have to constantly monitor the changes and try to tailor the vaccine as the virus mutates. They can't wait to see which one comes next.
The urgency stems from fears that H5N1 will combine with a human flu virus, creating a pathogen(病原体) that could be transmitted from person to person. But if people have no immunity to the virus, the strain may not mutate as rapidly in people as it does in birds.
To quickly generate the vaccine, researchers are using reverse genetics, which allows them to skip the long process of searching through reassorted viruses for the correct genetic combination. Instead, scientists clone sequences for hemagglutinin(红血球凝聚素) and neuraminidase(神经氨酸苷酶), the two key proteins in the virus. The sequences are then combined with human influenza genes to create a customized reference strain.
Because products developed with reverse genetics have never been tested in humans, the candidate vaccines will first have to clear regulatory review. In anticipation, the US Food and Drug Administration (FDA) and the European Agency for the Evaluation of Medicinal Products (EMEA) are both preparing pandemic response plans. The EMEA has produced a fist-track licensing program, an industry task force and detailed guidance for potential applicants.
In Europe, a reassortant influenza virus—but not the inactivated vaccine—produced by reverse genetics would be considered a genetically modified organism, and manufacturers would need approval from their national or local safety authorities. The WHO has prepared a preliminary biosafety risk assessment of pilot-lot vaccine, which could help speed up the review.
A preliminary version of their protocol calls for several hundred subjects, beginning with a group of young adults and gradually expanding to include those most susceptible to the flu—children and the elderly". If we had product", says Lambert", it would probably be a couple of months at the earliest before we have early data in healthy adults".
We can infer from Paragraph 2 that facing the tough task the researchers of WHO ______.
A．flinch from their work.
B．hesitate and feel perplexed.
C．carry on their research.
D．abandon their research.
第5题
American interest lies mainly in South Africa, by far the largest economy in the region. Services account for 60% of its GDP, and it increasingly dominates the rest of Africa in banking, information technology, telecom, retail' and other areas. Just as British banks, such as Barclays, have moved their African headquarters to South Africa over the past year, American investors see the country as a platform. to the rest of the continent.
Agreeing investment rules and resolving differences on intellectual property rights are the most urgent issues. American drug firms want to be part of the fast expansion in South Africa of production of anti-retroviral drugs, used against AIDS. By 2007 South Africa alone expects 1.2m patients to take the drugs daily. The country might be the world's biggest exporter of anti-AIDS drugs within a few years. Striking a bilateral deal now should make American investments easier.
But Mr. Zoellick's greater concern is for multilateral trade talks that stalled in Cancun, Mexico, in September. Alec Erwin, his South African counterpart, helped to organize the G20 group of poor and middle-income countries that opposed joint American-EU proposals there; he is widely tipped to take over as head of the World Trade Organization late next year, and would be a useful ally.
So Mr. Zoellick is trying to charm his African partner by agreeing to drop support for most of a group of issues (known as "Singapore" issues) that jammed up the talks at Cancun, and were opposed by poor countries; he says he also favors abolishing export subsidies in America--though only if Japan and the EU agree to do the same. That would please African exporters who say such subsidies destroy markets for their goods.
Mr. Zoellick's efforts to make more friends may be paying off. Even though America has treated Africa very shabbily on trade in the past, Mr. Erwin hints it is easier doing business with America than with Europe or Japan. A small sign, but perhaps a telling one.
It can be inferred from the first paragraph that ______.
A．6,000 goods from Africa are tariff-free to American countries
B．preferential export rules are interesting to southern Africans
C．most clothes found in the U.S. are actually made by Chinese
D．Lesotho is willing to export more agricultural goods to the U.S.
第6题
（英语专业必做）
Drunken driving—sometimes called America's socially accepted form. of murder— has become a national epidemic. Every hour of every day about three Americans on average are killed by drunken drivers, adding up to an incredible 250,000 over the past decade.
Heavy drinking used to be an acceptable part of the American macho (男子汉) image and judges were lenient in most courts, but the drunken slaughter has recently caused so many well-publicized tragedies, especially involving your children, that public opinion is no longer so tolerant.
Twenty states have raised the legal drinking age to 21, reversing a trend in the 1960s to reduce it to 18. After New Jersey lowered it to 18, the number of people killed by 18—20-year-old drivers more than doubled, so the state recently tipped it back to 21.
Reformers, however, fear raising the drinking age will have little effect unless accompanied by educational programs to help young people to develop "responsible attitude" about drinking and teach them to resist peer pleasure to drink.
New laws have led to increased arrests and tests in many areas already, to a marked decline in fatalities. Some states are also penalizing bars for serving customers too many drinks. A tavern (酒栈) in Massachusetts was fined for serving six or more brandies to a customer who was "obviously intoxicated" and later drove off the road, killing a nine-year-old boy.
As the fatalities continue to occur daily in every state, some Americans are even beginning to think well of the 13 years of national prohibition of alcohol that began in 1919, which President Hoover called the " noble experiment". They forgot that legal prohibition didn't stop drinking, but encouraged political corruption and organized crime. As with the becoming drug trade, there is no easy solution.
Drunken driving has become a serious problem in America because______.
A．most drunken drivers drive their cars at top speed
B．most drivers regard heavy drinking are part of the American macho image
C．fatalities caused by drunken driving have been gready increased
D．about 25 ,000 people on average are killed every year by drunken drivers
第7题
After the holiday makers were warned of a rockslide, they all ______.
A．ran to it
B．ran for it
C．ran from it
D．ran away off it
第8题
A.species
B.spacious
C.space
D.spaciously
第9题
One change in the early 1980s is a questioning of the permissive moral climate of recent years. More young people, while hesitant to preach or to condemn their peers, cite the destructive effects of the drugs and alcohol that are so widely available in the schools. It is peer pressure that pushes teenagers into drugs, but now the habit often is dropped after high school, according to Debbie Bishop, a 22-year-old secretary. James Elrod, a college junior in Kentucky, also reports that use of marijuana on campus has lessened. A Cornell University law student reflects the views of many with the comment: "I think that drug abuse is harmful to your own health and those around you". But he adds: "Drinking is fine only as long as it's not done to excess".
With the added pressures of a more uncertain world, most young people stress the importance of a healthy family life. Yet, as they look at the family's breakup that has taken place in the past decade, they concede that the challenge for many is to make the best of one-parent families. "The American family is evolving and changing, "according to Nina Mule, "Women are going out into the world and having careers. They're becoming more independent instead of being the burden of the family". "But a great need remains for a family structure, "says Nina, who still lives with her parents, "because people have to be able to survive emotionally". In Atlanta, 18-year-old Liss Joiner feels strongly about what's happened to the family". People have realized that the family has disintegrated, "she says, "But today's family—particularly the black family—is trying to pull itself together and become the strong unit as it once was. "A similar view is expressed by a senior at Brigham Young University: "A happy family means everything to me. I read a lot about how the American family is falling a part. But I see lots of strong families around me, and that makes me very optimistic".
Which of the following is NOT a feature of young people in the early 1980s？
A．The are more thoughtful and serious.
B．They have concern for the future of the country.
C．They have a yearning for the traditions.
D．They don't like adult world.
